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PSA Risk Score

Stockholm3

Stockholm3 is a PSA test for the early detection of treatment-requiring prostate cancer by combining several biomarkers and clinical data in an algorithm with the aim of providing a more qualitative risk assessment regarding prostate cancer. And with a higher precision, which results in reducing overdiagnosis and indicating detection of prostate cancer requiring treatment.

S3P

Stockholm3

PSA-test

3 195 kr

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Contents

Stockholm3 PSA test with risk assessment

Unlike traditional PSA tests, which only measure the levels of prostate-specific antigen, Stockholm3 uses an advanced algorithm to analyze a wider set of data.

Stockholm3 is a combination of biomarkers in blood samples (total PSA, free PSA, hK2, MSMB, MIC1 and 101 genetic markers) and anamnestic data: age, previous prostate biopsy and heredity for prostate cancer.

This makes it possible to detect more cancer cases requiring treatment and reduce the number of unnecessary biopsies. Stockholm3 is used for prostate cancer screening and offers a more reliable method for early detection and treatment.

Based on data from over 75,000 men, the results from Stockholm3 have been published in prestigious scientific journals such as The Lancet Oncology and European Urology.

Components of the Stockholm3 test

  • Biomarkers: Stockholm3 analyzes several protein markers, including PSA, hK2, MSMB and MIC-1.
  • Genetic markers: Analysis of genetic variants linked to an increased risk of prostate cancer.
  • Clinical data: Factors such as age, family history of prostate cancer and previous biopsy results are included.
  • Algorithm: An advanced algorithm compiles data from biomarkers, genetic markers and clinical factors to provide an individual risk score.

Stockholm3 Risk Score

The result of the Stockholm3 test is a Risk Score that indicates the risk of prostate cancer requiring treatment. The test also provides a recommendation for continued treatment based on the risk assessment.

Advantages of Stockholm3 compared to the PSA test

  • Higher precision: Stockholm3 finds twice as many cancer cases requiring treatment compared to the PSA test in clinical routine.
  • Reduced overdiagnosis: The test effectively distinguishes between treatment-requiring and indolent (harmless) cancer, reducing the number of unnecessary biopsies by 50 percent.
  • Early detection: Early detection of prostate cancer requiring treatment improves the chances of successful treatment and can save lives.

Reduced side effects

As Stockholm3 reduces the number of unnecessary biopsies, the risk of side effects such as sepsis, blood in urine and stool, which are common complications of prostate biopsies, is also reduced. This means that many men do not have to undergo unnecessary and potentially harmful interventions.

Use in clinical practice

  • Screening: Stockholm3 can be used for general screening of men over the age of 50 to identify those who have a higher risk of prostate cancer requiring treatment.
  • Follow-up: For men with previously elevated PSA levels or those who have already been treated for prostate cancer, Stockholm3 can provide more detailed information as a basis for follow-up and treatment decisions.

Summary of Stockholm3 analysis

The analysis of Stockholm3 is carried out in several different steps:

  • Analysis for total PSA: First, the level of total PSA in the blood is measured.
  • Additional analyses: If total PSA is ≥ 1.5 ng/ml, additional proteins and genetic changes are analyzed.
  • Calculation of results: Based on the results of these analyzes and clinical data, the following is calculated:
    • Stockholm3 Risk Score
    • Stockholm3 Prostate Volume cut-off
    • Stockholm3 Recommendation

Tests containing the marker Stockholm3

Health checks

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Prostate Check – MRI & Stockholm3

Prostate Check – MRI & Stockholm3

MRI Prostate + Stockholm3
Marker Icon 2 Biomarkers
  • MRI of the prostate with IV contrast.
  • Combined with advanced blood testing.
  • Detects cancer at an early stage.
  • Distinguishes benign from malignant.
  • Identifies inflammation and enlarged prostate.

10 599 kr

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Information

Medical comment included

With us, you will always receive a doctor’s opinion from a licensed physician when you order a medical check-up that includes a medical opinion. The doctor’s opinion includes an overall assessment of your results from laboratory analysis. The opinion is individual and may vary depending on the specific tests your medical check-up includes.

What can I expect in the medical report?

The medical opinion will summarize the results of your test results to give you an assessment of your health including any abnormalities outside the reference ranges. In case of abnormalities or need, your doctor may also contact you for a free conversation to explain and talk about your results. Remember that a health check always includes specific test results based on your health and your personal circumstances. Values outside the reference range should therefore always be discussed with a doctor before any decisions regarding possible treatment are made.

What does the doctor look at during a health check?

When assessing a blood test or health check, your doctor will look at several different parameters to evaluate your health and identify any abnormalities. Below are some common aspects your doctor may examine:

Blood counts: Your doctor will check red, white and platelet counts to identify any signs of anaemia, infection or bleeding.

Nutrients and biochemical markers: Includes, for example, analysis and monitoring of blood sugar (glucose) levels, electrolyte levels (e.g. sodium, potassium), liver function tests (e.g. liver enzymes), kidney function tests (e.g. creatinine, urea) and lipid profile (e.g. cholesterol, triglycerides). The results of the tests give your doctor a better idea of your organ function, blood sugar level, cholesterol conditions and other important health aspects.

Inflammatory markers: Your doctor may measure health markers such as C-reactive protein (CRP) or red blood cell decrease rate (SR) to evaluate inflammatory conditions or confirm an active infection.

Hormone levels: Your doctor may monitor your hormone levels to assess hormonal imbalances or diseases, such as thyroid hormones (TSH, T3, T4), sex hormones or other specific hormones such as testosterone levels.

Specific tests: Depending on your goal of your health check or medical history, your doctor may look into specific tests to investigate conditions or diseases, such as diabetes, vitamin deficiency or autoimmune diseases.

In conclusion, the doctor weighs all test results based on the health check to assess your overall health, detect any abnormalities and identify possible underlying medical conditions.

What happens if I have abnormal test results?

If your blood count is abnormal, this will be addressed in your personal medical opinion. Depending on the nature and extent of the abnormality, your doctor may also contact you directly through the test result service for further guidance. Various measures and advice will be provided based on the specific abnormalities observed along with your medical history.

  • Stockholm3 PSA test.
  • Analysis of several PSA markers.
  • Risk assessment for prostate cancer.

3 195 kr

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